"Endothelin-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 21-amino acid peptide produced in a variety of tissues including endothelial and vascular smooth-muscle cells, neurons and astrocytes in the central nervous system, and endometrial cells. It acts as a modulator of vasomotor tone, cell proliferation, and hormone production. (N Eng J Med 1995;333(6):356-63)
Descriptor ID |
D019332
|
MeSH Number(s) |
D12.644.276.400.225 D12.776.467.400.225 D23.529.400.225
|
Concept/Terms |
Proendothelin (1-38)- Proendothelin (1-38)
- Big Endothelin
- Big Endothelin-1
- Big Endothelin 1
- Endothelin-1, Big
- Endothelin, Big
Preproendothelin-1- Preproendothelin-1
- Preproendothelin 1
- Preproendothelin
- Proendothelin-1 Precursor
- Precursor, Proendothelin-1
- Proendothelin 1 Precursor
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Below are MeSH descriptors whose meaning is more general than "Endothelin-1".
Below are MeSH descriptors whose meaning is more specific than "Endothelin-1".
This graph shows the total number of publications written about "Endothelin-1" by people in this website by year, and whether "Endothelin-1" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2008 | 0 | 1 | 1 |
2012 | 1 | 0 | 1 |
2019 | 1 | 0 | 1 |
2022 | 2 | 0 | 2 |
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Below are the most recent publications written about "Endothelin-1" by people in Profiles.
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Associations of the vasoactive peptides CT-proET-1 and MR-proADM with incident type 2 diabetes: results from the BiomarCaRE Consortium. Cardiovasc Diabetol. 2022 06 09; 21(1):99.
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Association of C-Terminal Pro-Endothelin-1 with Mortality in the Population-Based KORA F4 Study. Vasc Health Risk Manag. 2022; 18:335-346.
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The G Protein-Coupled Bile Acid Receptor TGR5 (Gpbar1) Modulates Endothelin-1 Signaling in Liver. Cells. 2019 11 19; 8(11).
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Vasoregulatory peptides pro-endothelin-1 and pro-adrenomedullin are associated with metabolic syndrome in the population-based KORA F4 study. Eur J Endocrinol. 2012 Dec; 167(6):847-53.
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Interference with PPARgamma signaling causes cerebral vascular dysfunction, hypertrophy, and remodeling. Hypertension. 2008 Apr; 51(4):867-71.