"Hyperhomocysteinemia" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Condition in which the plasma levels of homocysteine and related metabolites are elevated (>13.9 μmol/l). Hyperhomocysteinemia can be familial or acquired. Development of the acquired hyperhomocysteinemia is mostly associated with vitamins B and/or folate deficiency (e.g., PERNICIOUS ANEMIA, vitamin malabsorption). Familial hyperhomocysteinemia often results in a more severe elevation of total homocysteine and excretion into the urine, resulting in HOMOCYSTINURIA. Hyperhomocysteinemia is a risk factor for cardiovascular and neurodegenerative diseases, osteoporotic fractures and complications during pregnancy.
| Descriptor ID |
D020138
|
| MeSH Number(s) |
C16.320.565.100.480 C18.452.603.378 C18.452.648.100.480 C18.654.521.500.133.699.418
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Hyperhomocysteinemia".
Below are MeSH descriptors whose meaning is more specific than "Hyperhomocysteinemia".
This graph shows the total number of publications written about "Hyperhomocysteinemia" by people in this website by year, and whether "Hyperhomocysteinemia" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Hyperhomocysteinemia" by people in Profiles.
-
Binding of copper is a mechanism of homocysteine toxicity leading to COX deficiency and apoptosis in primary neurons, PC12 and SHSY-5Y cells. Neurobiol Dis. 2006 Sep; 23(3):725-30.
MeSH information
