"Interleukin-4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A soluble factor produced by activated T-LYMPHOCYTES that induces the expression of MHC CLASS II GENES and FC RECEPTORS on B-LYMPHOCYTES and causes their proliferation and differentiation. It also acts on T-lymphocytes, MAST CELLS, and several other hematopoietic lineage cells.
| Descriptor ID |
D015847
|
| MeSH Number(s) |
D12.644.276.374.465.186 D12.776.467.374.465.178 D23.529.374.465.186
|
| Concept/Terms |
Interleukin-4- Interleukin-4
- Interleukin 4
- B-Cell Growth Factor-1
- B Cell Growth Factor 1
- B-Cell Growth Factor-I
- B Cell Growth Factor I
- B-Cell Proliferating Factor
- B Cell Proliferating Factor
- B-Cell Stimulating Factor-1
- B Cell Stimulating Factor 1
- B-Cell Stimulatory Factor 1
- B-Cell Stimulatory Factor-1
- BCGF-1
- Binetrakin
- BSF-1
- IL-4
- IL4
- Mast Cell Growth Factor-2
- Mast Cell Growth Factor 2
- MCGF-2
- B Cell Stimulatory Factor-1
- B Cell Stimulatory Factor 1
|
Below are MeSH descriptors whose meaning is more general than "Interleukin-4".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-4".
This graph shows the total number of publications written about "Interleukin-4" by people in this website by year, and whether "Interleukin-4" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Interleukin-4" by people in Profiles.
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Single-Cell Transcriptomics Analyses of Neural Stem Cell Heterogeneity and Contextual Plasticity in a Zebrafish Brain Model of Amyloid Toxicity. Cell Rep. 2019 04 23; 27(4):1307-1318.e3.
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3D Culture Method for Alzheimer's Disease Modeling Reveals Interleukin-4 Rescues A?42-Induced Loss of Human Neural Stem Cell Plasticity. Dev Cell. 2018 07 02; 46(1):85-101.e8.
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Cellular Differentiation of Human Monocytes Is Regulated by Time-Dependent Interleukin-4 Signaling and the Transcriptional Regulator NCOR2. Immunity. 2017 12 19; 47(6):1051-1066.e12.
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IL4/STAT6 Signaling Activates Neural Stem Cell Proliferation and Neurogenesis upon Amyloid-?42 Aggregation in Adult Zebrafish Brain. Cell Rep. 2016 10 18; 17(4):941-948.
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GM-CSF-licensed CD11b+ lung dendritic cells orchestrate Th2 immunity to Blomia tropicalis. J Immunol. 2014 Jul 15; 193(2):496-509.
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Cytokine-dependent regulation of dendritic cell differentiation in the splenic microenvironment. Eur J Immunol. 2014 Feb; 44(2):500-10.
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Production and release of macrophage migration inhibitory factor from human adipocytes. Endocrinology. 2005 Mar; 146(3):1006-11.
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Autologous tumor infiltrating T cells cytotoxic for follicular lymphoma cells can be expanded in vitro. Blood. 1997 May 15; 89(10):3806-16.
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Pre-B acute lymphoblastic leukemia cells may induce T-cell anergy to alloantigen. Blood. 1996 Jul 01; 88(1):41-8.
MeSH information
