"Receptor, Insulin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cell surface receptor for INSULIN. It comprises a tetramer of two alpha and two beta subunits which are derived from cleavage of a single precursor protein. The receptor contains an intrinsic TYROSINE KINASE domain that is located within the beta subunit. Activation of the receptor by INSULIN results in numerous metabolic changes including increased uptake of GLUCOSE into the liver, muscle, and ADIPOSE TISSUE.
| Descriptor ID |
D011972
|
| MeSH Number(s) |
D08.811.913.696.620.682.725.400.200 D12.776.543.750.630.484 D12.776.543.750.750.580.300
|
| Concept/Terms |
Receptor, Insulin- Receptor, Insulin
- Receptors, Insulin
- Insulin Receptors
- Insulin Receptor Protein-Tyrosine Kinase
- Insulin Receptor Protein Tyrosine Kinase
- Insulin Receptor
- Insulin-Dependent Tyrosine Protein Kinase
|
Below are MeSH descriptors whose meaning is more general than "Receptor, Insulin".
Below are MeSH descriptors whose meaning is more specific than "Receptor, Insulin".
This graph shows the total number of publications written about "Receptor, Insulin" by people in this website by year, and whether "Receptor, Insulin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptor, Insulin" by people in Profiles.
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Ultra-rapid emergency genomic diagnosis of Donahue syndrome in a preterm infant within 17?hours. Am J Med Genet A. 2021 01; 185(1):90-96.
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Temperature and insulin signaling regulate body size in Hydra by the Wnt and TGF-beta pathways. Nat Commun. 2019 07 22; 10(1):3257.
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Regulation of Insulin Receptor Trafficking by Bardet Biedl Syndrome Proteins. PLoS Genet. 2015 Jun; 11(6):e1005311.
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Autosomal recessive isolated familial acanthosis nigricans in a Pakistani family due to a homozygous mutation in the insulin receptor gene. Br J Dermatol. 2013 Aug; 169(2):476-8.
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[Study on the insulin and insulin receptor in the progression of renal ischemic and reperfusion]. Sichuan Da Xue Xue Bao Yi Xue Ban. 2003 Oct; 34(4):660-2.
MeSH information
