"Multigene Family" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A set of genes descended by duplication and variation from some ancestral gene. Such genes may be clustered together on the same chromosome or dispersed on different chromosomes. Examples of multigene families include those that encode the hemoglobins, immunoglobulins, histocompatibility antigens, actins, tubulins, keratins, collagens, heat shock proteins, salivary glue proteins, chorion proteins, cuticle proteins, yolk proteins, and phaseolins, as well as histones, ribosomal RNA, and transfer RNA genes. The latter three are examples of reiterated genes, where hundreds of identical genes are present in a tandem array. (King & Stanfield, A Dictionary of Genetics, 4th ed)
Descriptor ID |
D005810
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MeSH Number(s) |
G05.360.340.024.340.645
|
Concept/Terms |
Multigene Family- Multigene Family
- Families, Multigene
- Family, Multigene
- Multigene Families
Gene Clusters- Gene Clusters
- Cluster, Gene
- Clusters, Gene
- Gene Cluster
|
Below are MeSH descriptors whose meaning is more general than "Multigene Family".
Below are MeSH descriptors whose meaning is more specific than "Multigene Family".
This graph shows the total number of publications written about "Multigene Family" by people in this website by year, and whether "Multigene Family" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1997 | 0 | 1 | 1 |
1998 | 0 | 1 | 1 |
2005 | 1 | 0 | 1 |
2006 | 1 | 2 | 3 |
2007 | 1 | 2 | 3 |
2008 | 1 | 2 | 3 |
2009 | 1 | 0 | 1 |
2010 | 0 | 3 | 3 |
2011 | 1 | 2 | 3 |
2012 | 0 | 1 | 1 |
2013 | 1 | 2 | 3 |
2016 | 0 | 2 | 2 |
2019 | 0 | 1 | 1 |
2020 | 0 | 1 | 1 |
2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Multigene Family" by people in Profiles.
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Unraveling Structural Rearrangements of the CFH Gene Cluster in Atypical Hemolytic Uremic Syndrome Patients Using Molecular Combing and Long-Fragment Targeted Sequencing. J Mol Diagn. 2022 06; 24(6):619-631.
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Genomewide Association Study of Severe Covid-19 with Respiratory Failure. N Engl J Med. 2020 10 15; 383(16):1522-1534.
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Clinical relevance of H-RAS, K-RAS, and N-RAS mRNA expression in primary breast cancer patients. Breast Cancer Res Treat. 2020 Jan; 179(2):403-414.
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Plasma miR-122 and miR-200 family are prognostic markers in colorectal cancer. Int J Cancer. 2017 Jan 01; 140(1):176-187.
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Structure and evolutionary history of a large family of NLR proteins in the zebrafish. Open Biol. 2016 Apr; 6(4):160009.
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The maize (Zea mays L.) AUXIN/INDOLE-3-ACETIC ACID gene family: phylogeny, synteny, and unique root-type and tissue-specific expression patterns during development. PLoS One. 2013; 8(11):e78859.
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A genomic-scale artificial microRNA library as a tool to investigate the functionally redundant gene space in Arabidopsis. Plant Cell. 2013 Aug; 25(8):2848-63.
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Genomes of Stigonematalean cyanobacteria (subsection V) and the evolution of oxygenic photosynthesis from prokaryotes to plastids. Genome Biol Evol. 2013; 5(1):31-44.
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The chromatin insulator CTCF and the emergence of metazoan diversity. Proc Natl Acad Sci U S A. 2012 Oct 23; 109(43):17507-12.
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Genome-wide significant association between alcohol dependence and a variant in the ADH gene cluster. Addict Biol. 2012 Jan; 17(1):171-80.