"Medulloblastoma" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A malignant neoplasm that may be classified either as a glioma or as a primitive neuroectodermal tumor of childhood (see NEUROECTODERMAL TUMOR, PRIMITIVE). The tumor occurs most frequently in the first decade of life with the most typical location being the cerebellar vermis. Histologic features include a high degree of cellularity, frequent mitotic figures, and a tendency for the cells to organize into sheets or form rosettes. Medulloblastoma have a high propensity to spread throughout the craniospinal intradural axis. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2060-1)
Descriptor ID |
D008527
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MeSH Number(s) |
C04.557.465.625.600.380.515 C04.557.465.625.600.590.500 C04.557.470.670.380.515 C04.557.470.670.590.500 C04.557.580.625.600.380.515 C04.557.580.625.600.590.500
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Concept/Terms |
Melanocytic Medulloblastoma- Melanocytic Medulloblastoma
- Medulloblastoma, Melanocytic
- Medulloblastomas, Melanocytic
- Melanocytic Medulloblastomas
Medulloblastoma, Childhood- Medulloblastoma, Childhood
- Childhood Medulloblastoma
- Childhood Medulloblastomas
- Medulloblastomas, Childhood
Arachnoidal Cerebellar Sarcoma, Circumscribed- Arachnoidal Cerebellar Sarcoma, Circumscribed
- Sarcoma, Cerebellar, Circumscribed Arachnoidal
- Medulloblastoma, Desmoplastic
- Desmoplastic Medulloblastoma
- Desmoplastic Medulloblastomas
- Medulloblastomas, Desmoplastic
Medulloblastoma, Adult- Medulloblastoma, Adult
- Adult Medulloblastoma
- Adult Medulloblastomas
- Medulloblastomas, Adult
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Below are MeSH descriptors whose meaning is more general than "Medulloblastoma".
Below are MeSH descriptors whose meaning is more specific than "Medulloblastoma".
This graph shows the total number of publications written about "Medulloblastoma" by people in this website by year, and whether "Medulloblastoma" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2010 | 1 | 0 | 1 |
2014 | 1 | 0 | 1 |
2018 | 3 | 0 | 3 |
2019 | 4 | 0 | 4 |
2020 | 1 | 0 | 1 |
2021 | 2 | 1 | 3 |
2022 | 2 | 0 | 2 |
2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Medulloblastoma" by people in Profiles.
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Tacedinaline (CI-994), a class I HDAC inhibitor, targets intrinsic tumor growth and leptomeningeal dissemination in MYC-driven medulloblastoma while making them susceptible to anti-CD47-induced macrophage phagocytosis via NF-kB-TGM2 driven tumor inflammation. J Immunother Cancer. 2023 01; 11(1).
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Intratumoral heterogeneity of MYC drives medulloblastoma metastasis and angiogenesis. Neuro Oncol. 2022 09 01; 24(9):1509-1523.
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The HHIP-AS1 lncRNA promotes tumorigenicity through stabilization of dynein complex 1 in human SHH-driven tumors. Nat Commun. 2022 07 13; 13(1):4061.
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Circular RNA profiling distinguishes medulloblastoma groups and shows aberrant RMST overexpression in WNT medulloblastoma. Acta Neuropathol. 2021 06; 141(6):975-978.
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An extracellular vesicle-related gene expression signature identifies high-risk patients in medulloblastoma. Neuro Oncol. 2021 04 12; 23(4):586-598.
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The Expression of the Cancer-Associated lncRNA Snhg15 Is Modulated by EphrinA5-Induced Signaling. Int J Mol Sci. 2021 Jan 29; 22(3).
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YBX1 Indirectly Targets Heterochromatin-Repressed Inflammatory Response-Related Apoptosis Genes through Regulating CBX5 mRNA. Int J Mol Sci. 2020 Jun 23; 21(12).
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Germline GPR161 Mutations Predispose to Pediatric Medulloblastoma. J Clin Oncol. 2020 01 01; 38(1):43-50.
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Low mutational load in pediatric medulloblastoma still translates into neoantigens as targets for specific T-cell immunotherapy. Cytotherapy. 2019 09; 21(9):973-986.
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Mutated SON putatively causes a cancer syndrome comprising high-risk medulloblastoma combined with caf?-au-lait spots. Fam Cancer. 2019 07; 18(3):353-358.