"Ion Channels" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Gated, ion-selective glycoproteins that traverse membranes. The stimulus for ION CHANNEL GATING can be due to a variety of stimuli such as LIGANDS, a TRANSMEMBRANE POTENTIAL DIFFERENCE, mechanical deformation or through INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS.
| Descriptor ID |
D007473
|
| MeSH Number(s) |
D12.776.157.530.400 D12.776.543.550.450 D12.776.543.585.400
|
| Concept/Terms |
Ion Channels- Ion Channels
- Channels, Ion
- Ionic Channels
- Channels, Ionic
- Membrane Channels
- Channels, Membrane
- Ionic Channel
- Channel, Ionic
- Ion Channel
- Channel, Ion
- Membrane Channel
- Channel, Membrane
|
Below are MeSH descriptors whose meaning is more general than "Ion Channels".
Below are MeSH descriptors whose meaning is more specific than "Ion Channels".
This graph shows the total number of publications written about "Ion Channels" by people in this website by year, and whether "Ion Channels" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2016 | 1 | 1 | 2 |
| 2018 | 1 | 1 | 2 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Ion Channels" by people in Profiles.
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Unique variants in CLCN3, encoding an endosomal anion/proton exchanger, underlie a spectrum of neurodevelopmental disorders. Am J Hum Genet. 2021 08 05; 108(8):1450-1465.
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Microangiopathy and mild mixed neuromyopathic alterations in a patient with homozygous PIEZO-2 mutation. Neuromuscul Disord. 2018 12; 28(12):1006-1011.
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Genetic variants in components of the NALCN-UNC80-UNC79 ion channel complex cause a broad clinical phenotype (NALCN channelopathies). Hum Genet. 2018 Sep; 137(9):753-768.
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Recessive PIEZO2 stop mutation causes distal arthrogryposis with distal muscle weakness, scoliosis and proprioception defects. J Hum Genet. 2017 Apr; 62(4):497-501.
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Exome sequencing identifies potential novel candidate genes in patients with unexplained colorectal adenomatous polyposis. Fam Cancer. 2016 Apr; 15(2):281-8.
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Loss of UCP2 attenuates mitochondrial dysfunction without altering ROS production and uncoupling activity. PLoS Genet. 2014 Jun; 10(6):e1004385.
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The mechanism of neuroprotection by topiramate in an animal model of epilepsy. Epilepsia. 2004 Dec; 45(12):1478-87.
MeSH information
