"DNA Helicases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Proteins that catalyze the unwinding of duplex DNA during replication by binding cooperatively to single-stranded regions of DNA or to short regions of duplex DNA that are undergoing transient opening. In addition DNA helicases are DNA-dependent ATPases that harness the free energy of ATP hydrolysis to translocate DNA strands.
| Descriptor ID |
D004265
|
| MeSH Number(s) |
D08.811.277.040.025.159 D08.811.399.340
|
| Concept/Terms |
DNA Helicases- DNA Helicases
- Helicases, DNA
- DNA Unwinding Proteins
- Unwinding Proteins, DNA
ATP-Dependent DNA Helicases- ATP-Dependent DNA Helicases
- ATP Dependent DNA Helicases
- DNA Helicases, ATP-Dependent
- Helicases, ATP-Dependent DNA
|
Below are MeSH descriptors whose meaning is more general than "DNA Helicases".
Below are MeSH descriptors whose meaning is more specific than "DNA Helicases".
This graph shows the total number of publications written about "DNA Helicases" by people in this website by year, and whether "DNA Helicases" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 1 | 0 | 1 |
| 2009 | 1 | 1 | 2 |
| 2011 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 2 | 3 |
| 2017 | 1 | 0 | 1 |
| 2018 | 0 | 2 | 2 |
| 2019 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
| 2022 | 0 | 2 | 2 |
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Below are the most recent publications written about "DNA Helicases" by people in Profiles.
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Primary cilia contribute to the aggressiveness of atypical teratoid/rhabdoid tumors. Cell Death Dis. 2022 Sep 20; 13(9):806.
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Clinical relevance of molecular characteristics in Burkitt lymphoma differs according to age. Nat Commun. 2022 07 06; 13(1):3881.
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Generation of an induced pluripotent stem cell line (IUFi001) from a Cockayne syndrome patient carrying a mutation in the ERCC6 gene. Stem Cell Res. 2021 08; 55:102456.
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Comparative RNAi Screens in Isogenic Human Stem Cells Reveal SMARCA4 as a Differential Regulator. Stem Cell Reports. 2019 05 14; 12(5):1084-1098.
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The mutational landscape of Burkitt-like lymphoma with 11q aberration is distinct from that of Burkitt lymphoma. Blood. 2019 02 28; 133(9):962-966.
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Linear mitochondrial DNA is rapidly degraded by components of the replication machinery. Nat Commun. 2018 04 30; 9(1):1727.
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Association Between Loss-of-Function Mutations Within the FANCM Gene and Early-Onset Familial Breast Cancer. JAMA Oncol. 2017 Sep 01; 3(9):1245-1248.
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FANCM c.5791C>T nonsense mutation (rs144567652) induces exon skipping, affects DNA repair activity and is a familial breast cancer risk factor. Hum Mol Genet. 2015 Sep 15; 24(18):5345-55.
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Mutational dynamics between primary and relapse neuroblastomas. Nat Genet. 2015 Aug; 47(8):872-7.
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Exome sequencing unravels unexpected differential diagnoses in individuals with the tentative diagnosis of Coffin-Siris and Nicolaides-Baraitser syndromes. Hum Genet. 2015 Jun; 134(6):553-68.
MeSH information
