"Digitonin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A glycoside obtained from Digitalis purpurea; the aglycone is digitogenin which is bound to five sugars. Digitonin solubilizes lipids, especially in membranes and is used as a tool in cellular biochemistry, and reagent for precipitating cholesterol. It has no cardiac effects.
| Descriptor ID |
D004072
|
| MeSH Number(s) |
D04.210.500.155.580.130.500.236 D09.408.180.261.236
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Digitonin".
Below are MeSH descriptors whose meaning is more specific than "Digitonin".
This graph shows the total number of publications written about "Digitonin" by people in this website by year, and whether "Digitonin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
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Below are the most recent publications written about "Digitonin" by people in Profiles.
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The contribution of thioredoxin-2 reductase and glutathione peroxidase to H(2)O(2) detoxification of rat brain mitochondria. Biochim Biophys Acta. 2012 Oct; 1817(10):1901-6.
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Oxygraphic evaluation of mitochondrial function in digitonin-permeabilized mononuclear cells and cultured skin fibroblasts of patients with chronic progressive external ophthalmoplegia. Biochem Mol Med. 1995 Apr; 54(2):105-11.
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Regulation of oxidative phosphorylation in mitochondria of epididymal bull spermatozoa. Biochim Biophys Acta. 1987 Aug 12; 893(1):100-8.
MeSH information
