"Epithelial Cell Adhesion Molecule" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cell adhesion molecule that is expressed on the membranes of nearly all EPITHELIAL CELLS, especially at the junctions between intestinal epithelial cells and intraepithelial LYMPHOCYTES. It also is expressed on the surface of ADENOCARCINOMA and epithelial tumor cells. It may function in the MUCOSA through homophilic interactions to provide a barrier against infection. It also regulates the proliferation and differentiation of EMBRYONIC STEM CELLS.
Descriptor ID |
D000071858
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MeSH Number(s) |
D12.776.395.550.200.263 D12.776.543.550.200.263 D23.050.285.357 D23.050.301.350.263
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Concept/Terms |
Epithelial Cell Adhesion Molecule- Epithelial Cell Adhesion Molecule
- CD326 Protein
- Antigen, CD326
- CD326 Antigen
- ESA Antigen
- Antigen, ESA
- EpCAM
- GA733 Antigen
- Antigen, GA733
- GA733 Tumor-Associated Antigen
- GA733 Tumor Associated Antigen
- Tumor-Associated Antigen, GA733
- Tacstd1 Protein
- Epithelial Specific Antigen
- Antigen, Epithelial Specific
- Ep-CAM
- Tumor-Associated Antigen GA733
- GA733, Tumor-Associated Antigen
- Tumor Associated Antigen GA733
- GA 733 Tumor-Associated Antigen
- GA 733 Tumor Associated Antigen
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Below are MeSH descriptors whose meaning is more general than "Epithelial Cell Adhesion Molecule".
Below are MeSH descriptors whose meaning is more specific than "Epithelial Cell Adhesion Molecule".
This graph shows the total number of publications written about "Epithelial Cell Adhesion Molecule" by people in this website by year, and whether "Epithelial Cell Adhesion Molecule" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2009 | 0 | 1 | 1 |
2012 | 0 | 1 | 1 |
2015 | 0 | 1 | 1 |
2017 | 2 | 0 | 2 |
2018 | 0 | 1 | 1 |
2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Epithelial Cell Adhesion Molecule" by people in Profiles.
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Comparative analysis of EpCAM high-expressing and low-expressing circulating tumour cells with regard to their clonal relationship and clinical value. Br J Cancer. 2023 05; 128(9):1742-1752.
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Filtration based assessment of CTCs and CellSearch? based assessment are both powerful predictors of prognosis for metastatic breast cancer patients. BMC Cancer. 2018 02 20; 18(1):204.
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A Novel Workflow to Enrich and Isolate Patient-Matched EpCAMhigh and EpCAMlow/negative CTCs Enables the Comparative Characterization of the PIK3CA Status in Metastatic Breast Cancer. Int J Mol Sci. 2017 Aug 31; 18(9).
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Enrichment, Isolation and Molecular Characterization of EpCAM-Negative Circulating Tumor Cells. Adv Exp Med Biol. 2017; 994:181-203.
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EpCAM-Independent Enrichment of Circulating Tumor Cells in Metastatic Breast Cancer. PLoS One. 2015; 10(12):e0144535.
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EPCAM-A novel molecular target for the treatment of pediatric and adult germ cell tumors. Genes Chromosomes Cancer. 2013 Jan; 52(1):24-32.
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Detection and characterization of circulating tumor cells in blood of primary breast cancer patients by RT-PCR and comparison to status of bone marrow disseminated cells. Breast Cancer Res. 2009; 11(4):R59.