"Insulin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).
| Descriptor ID |
D007328
|
| MeSH Number(s) |
D06.472.699.587.200.500.625 D12.644.548.586.200.500.625
|
| Concept/Terms |
Insulin- Insulin
- Insulin, Regular
- Regular Insulin
- Soluble Insulin
- Insulin, Soluble
|
Below are MeSH descriptors whose meaning is more general than "Insulin".
Below are MeSH descriptors whose meaning is more specific than "Insulin".
This graph shows the total number of publications written about "Insulin" by people in this website by year, and whether "Insulin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 2003 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 3 | 2 | 5 |
| 2008 | 0 | 2 | 2 |
| 2010 | 1 | 3 | 4 |
| 2012 | 1 | 2 | 3 |
| 2013 | 0 | 3 | 3 |
| 2014 | 2 | 1 | 3 |
| 2015 | 1 | 6 | 7 |
| 2016 | 3 | 3 | 6 |
| 2017 | 1 | 3 | 4 |
| 2018 | 1 | 1 | 2 |
| 2019 | 3 | 2 | 5 |
| 2020 | 0 | 1 | 1 |
| 2021 | 1 | 5 | 6 |
| 2023 | 0 | 4 | 4 |
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Below are the most recent publications written about "Insulin" by people in Profiles.
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Associations of plasma proteomics with type 2 diabetes and related traits: results from the longitudinal KORA S4/F4/FF4 Study. Diabetologia. 2023 09; 66(9):1655-1668.
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Ageing-associated changes in transcriptional elongation influence longevity. Nature. 2023 Apr; 616(7958):814-821.
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Metabolic surgery-induced changes of the growth hormone system relate to improved adipose tissue function. Int J Obes (Lond). 2023 06; 47(6):505-511.
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Loci for insulin processing and secretion provide insight into type 2 diabetes risk. Am J Hum Genet. 2023 02 02; 110(2):284-299.
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Multi-omics profiling of living human pancreatic islet donors reveals heterogeneous beta cell trajectories towards type 2 diabetes. Nat Metab. 2021 07; 3(7):1017-1031.
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Pancreatic fat cells of humans with type 2 diabetes display reduced adipogenic and lipolytic activity. Am J Physiol Cell Physiol. 2021 06 01; 320(6):C1000-C1012.
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Reduced Muscle Strength Is Associated With Insulin Resistance in Type 2 Diabetes Patients With Osteoarthritis. J Clin Endocrinol Metab. 2021 03 25; 106(4):1062-1073.
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The hepatokine fetuin-A disrupts functional maturation of pancreatic beta cells. Diabetologia. 2021 06; 64(6):1358-1374.
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Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability. Nat Commun. 2021 01 05; 12(1):24.
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Longitudinal associations between ambient air pollution and insulin sensitivity: results from the KORA cohort study. Lancet Planet Health. 2021 01; 5(1):e39-e49.
MeSH information
