"Bone Morphogenetic Protein 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A bone morphogenetic protein family member that includes an active tolloid-like metalloproteinase domain. The metalloproteinase activity of bone morphogenetic protein 1 is specific for the removal of the C-propeptide of PROCOLLAGEN and may act as a regulator of EXTRACELLULAR MATRIX deposition. Alternative splicing of MRNA for bone morphogenetic protein 1 results in the production of several PROTEIN ISOFORMS.
| Descriptor ID |
D055395
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| MeSH Number(s) |
D08.811.277.656.300.480.525.700.049 D08.811.277.656.675.374.525.700.900.500 D12.644.276.848.049 D12.644.276.948.500 D12.644.276.954.200.100 D12.776.467.836.049 D12.776.467.942.200.100 D12.776.467.948.500 D23.529.942.200.100 D23.529.948.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Bone Morphogenetic Protein 1".
Below are MeSH descriptors whose meaning is more specific than "Bone Morphogenetic Protein 1".
This graph shows the total number of publications written about "Bone Morphogenetic Protein 1" by people in this website by year, and whether "Bone Morphogenetic Protein 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
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Below are the most recent publications written about "Bone Morphogenetic Protein 1" by people in Profiles.
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Attenuated BMP1 function compromises osteogenesis, leading to bone fragility in humans and zebrafish. Am J Hum Genet. 2012 Apr 06; 90(4):661-74.
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Loss of the BMP antagonist, SMOC-1, causes Ophthalmo-acromelic (Waardenburg Anophthalmia) syndrome in humans and mice. PLoS Genet. 2011 Jul; 7(7):e1002114.
MeSH information
