"Leptin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 16-kDa peptide hormone secreted from WHITE ADIPOCYTES. Leptin serves as a feedback signal from fat cells to the CENTRAL NERVOUS SYSTEM in regulation of food intake, energy balance, and fat storage.
| Descriptor ID |
D020738
|
| MeSH Number(s) |
D06.472.699.042.500 D12.644.276.024.500 D12.644.548.011.500 D12.776.467.024.500 D23.529.024.500
|
| Concept/Terms |
Leptin- Leptin
- Obese Protein
- Obese Gene Product
- Gene Product, Obese
- Ob Gene Product
- Gene Product, Ob
- Ob Protein
|
Below are MeSH descriptors whose meaning is more general than "Leptin".
Below are MeSH descriptors whose meaning is more specific than "Leptin".
This graph shows the total number of publications written about "Leptin" by people in this website by year, and whether "Leptin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Leptin" by people in Profiles.
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Metabolic surgery-induced changes of the growth hormone system relate to improved adipose tissue function. Int J Obes (Lond). 2023 06; 47(6):505-511.
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Inflammatory mediators in the adipo-renal axis: leptin, adiponectin, and soluble ICAM-1. Am J Physiol Renal Physiol. 2020 09 01; 319(3):F469-F475.
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Leptin gene polymorphisms are associated with weight gain during lithium augmentation in patients with major depression. Eur Neuropsychopharmacol. 2019 12; 29(2):211-221.
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Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels. Nat Commun. 2016 Feb 01; 7:10494.
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Association of adiponectin and leptin with relative telomere length in seven independent cohorts including 11,448 participants. Eur J Epidemiol. 2014 Sep; 29(9):629-38.
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Proinflammatory cytokines, adiponectin, and increased risk of primary cardiovascular events in diabetic patients with or without renal dysfunction: results from the ESTHER study. Diabetes Care. 2013 Jun; 36(6):1703-11.
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Leptin, adiponectin, their ratio and risk of Coronary Heart Disease: results from the MONICA/KORA Augsburg Study 1984-2002. Atherosclerosis. 2010 Mar; 209(1):220-5.
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In situ profiling of adipokines in subcutaneous microdialysates from lean and obese individuals. Am J Physiol Endocrinol Metab. 2008 Nov; 295(5):E1095-105.
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Relationship between adipocyte size and adipokine expression and secretion. J Clin Endocrinol Metab. 2007 Mar; 92(3):1023-33.
MeSH information
