"Tropomyosin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A protein found in the thin filaments of muscle fibers. It inhibits contraction of the muscle unless its position is modified by TROPONIN.
Descriptor ID |
D014335
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MeSH Number(s) |
D05.750.078.730.800 D12.776.210.500.895 D12.776.220.525.800
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Tropomyosin".
Below are MeSH descriptors whose meaning is more specific than "Tropomyosin".
This graph shows the total number of publications written about "Tropomyosin" by people in this website by year, and whether "Tropomyosin" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1994 | 1 | 0 | 1 |
1995 | 1 | 0 | 1 |
1998 | 2 | 1 | 3 |
1999 | 2 | 0 | 2 |
2000 | 1 | 0 | 1 |
2001 | 1 | 0 | 1 |
2013 | 1 | 0 | 1 |
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Below are the most recent publications written about "Tropomyosin" by people in Profiles.
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In-depth proteomic analysis of human tropomyosin by top-down mass spectrometry. J Muscle Res Cell Motil. 2013 Aug; 34(3-4):199-210.
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A familial hypertrophic cardiomyopathy alpha-tropomyosin mutation causes severe cardiac hypertrophy and death in mice. J Mol Cell Cardiol. 2001 Oct; 33(10):1815-28.
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Tropomyosin 3 increases striated muscle isoform diversity. Biochemistry. 2000 Jul 18; 39(28):8291-7.
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Rescue of high expression beta-tropomyosin transgenic mice by 5-propyl-2-thiouracil. Regulating the alpha-myosin heavy chain promoter. J Biol Chem. 1999 Oct 08; 274(41):29558-63.
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Mouse model of a familial hypertrophic cardiomyopathy mutation in alpha-tropomyosin manifests cardiac dysfunction. Circ Res. 1999 Jul 09; 85(1):47-56.
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Prevention of cardiac hypertrophy in mice by calcineurin inhibition. Science. 1998 Sep 11; 281(5383):1690-3.
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Beta-tropomyosin overexpression induces severe cardiac abnormalities. J Mol Cell Cardiol. 1998 Aug; 30(8):1545-57.
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Molecular and physiological effects of alpha-tropomyosin ablation in the mouse. Circ Res. 1998 Jan 9-23; 82(1):116-23.
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Molecular and physiological effects of overexpressing striated muscle beta-tropomyosin in the adult murine heart. J Biol Chem. 1995 Dec 22; 270(51):30593-603.
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Hydra tropomyosin TROP1 is expressed in head-specific epithelial cells and is a major component of the cytoskeletal structure that anchors nematocytes. J Cell Sci. 1994 Jun; 107 ( Pt 6):1403-11.