"tau Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Microtubule-associated proteins that are mainly expressed in neurons. Tau proteins constitute several isoforms and play an important role in the assembly of tubulin monomers into microtubules and in maintaining the cytoskeleton and axonal transport. Aggregation of specific sets of tau proteins in filamentous inclusions is the common feature of intraneuronal and glial fibrillar lesions (NEUROFIBRILLARY TANGLES; NEUROPIL THREADS) in numerous neurodegenerative disorders (ALZHEIMER DISEASE; TAUOPATHIES).
Descriptor ID |
D016875
|
MeSH Number(s) |
D12.776.220.600.450.510 D12.776.631.560.510
|
Concept/Terms |
tau Proteins- tau Proteins
- Proteins, tau
- tau Protein
- Protein, tau
|
Below are MeSH descriptors whose meaning is more general than "tau Proteins".
Below are MeSH descriptors whose meaning is more specific than "tau Proteins".
This graph shows the total number of publications written about "tau Proteins" by people in this website by year, and whether "tau Proteins" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2014 | 1 | 0 | 1 |
2019 | 1 | 0 | 1 |
2020 | 0 | 1 | 1 |
2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "tau Proteins" by people in Profiles.
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New insights into the genetic etiology of Alzheimer's disease and related dementias. Nat Genet. 2022 04; 54(4):412-436.
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SARS-CoV-2 targets neurons of 3D human brain organoids. EMBO J. 2020 10 15; 39(20):e106230.
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Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates A?, tau, immunity and lipid processing. Nat Genet. 2019 03; 51(3):414-430.
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SUCLG2 identified as both a determinator of CSF A?1-42 levels and an attenuator of cognitive decline in Alzheimer's disease. Hum Mol Genet. 2014 Dec 15; 23(24):6644-58.