"Serotonin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A biochemical messenger and regulator, synthesized from the essential amino acid L-TRYPTOPHAN. In humans it is found primarily in the central nervous system, gastrointestinal tract, and blood platelets. Serotonin mediates several important physiological functions including neurotransmission, gastrointestinal motility, hemostasis, and cardiovascular integrity. Multiple receptor families (RECEPTORS, SEROTONIN) explain the broad physiological actions and distribution of this biochemical mediator.
Descriptor ID |
D012701
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MeSH Number(s) |
D02.092.211.215.801.852 D03.633.100.473.914.814 D23.469.050.650
|
Concept/Terms |
Serotonin- Serotonin
- 5-Hydroxytryptamine
- 5 Hydroxytryptamine
- Hippophaine
- 3-(2-Aminoethyl)-1H-indol-5-ol
- Enteramine
- 5-HT
|
Below are MeSH descriptors whose meaning is more general than "Serotonin".
Below are MeSH descriptors whose meaning is more specific than "Serotonin".
This graph shows the total number of publications written about "Serotonin" by people in this website by year, and whether "Serotonin" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2008 | 0 | 1 | 1 |
2013 | 0 | 1 | 1 |
2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Serotonin" by people in Profiles.
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The serotonin receptor 3E variant is a risk factor for female IBS-D. J Mol Med (Berl). 2022 Nov; 100(11):1617-1627.
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aCaMKII autophosphorylation controls the establishment of alcohol drinking behavior. Neuropsychopharmacology. 2013 Aug; 38(9):1636-47.
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Interference with PPARgamma signaling causes cerebral vascular dysfunction, hypertrophy, and remodeling. Hypertension. 2008 Apr; 51(4):867-71.
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Investigation into the age-dependence of release of serotonin and noradrenaline in the rat brain cortex and of autoreceptor-mediated modulation of release. Neuropharmacology. 1989 Aug; 28(8):811-5.
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Histamine H3 receptor-mediated inhibition of serotonin release in the rat brain cortex. Naunyn Schmiedebergs Arch Pharmacol. 1988 May; 337(5):588-90.