"RNA Polymerase III" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A DNA-dependent RNA polymerase present in bacterial, plant, and animal cells. It functions in the nucleoplasmic structure where it transcribes DNA into RNA. It has specific requirements for cations and salt and has shown an intermediate sensitivity to alpha-amanitin in comparison to RNA polymerase I and II.
Descriptor ID |
D012320
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MeSH Number(s) |
D08.811.913.696.445.735.270.775
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Concept/Terms |
RNA Polymerase III- RNA Polymerase III
- Polymerase III, RNA
- DNA-Dependent RNA Polymerase III
- DNA Dependent RNA Polymerase III
- RNA Polymerase C
- Polymerase C, RNA
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Below are MeSH descriptors whose meaning is more general than "RNA Polymerase III".
Below are MeSH descriptors whose meaning is more specific than "RNA Polymerase III".
This graph shows the total number of publications written about "RNA Polymerase III" by people in this website by year, and whether "RNA Polymerase III" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2010 | 1 | 0 | 1 |
2015 | 1 | 0 | 1 |
2017 | 1 | 0 | 1 |
2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "RNA Polymerase III" by people in Profiles.
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Analyses of LMNA-negative juvenile progeroid cases confirms biallelic POLR3A mutations in Wiedemann-Rautenstrauch-like syndrome and expands the phenotypic spectrum of PYCR1 mutations. Hum Genet. 2018 Dec; 137(11-12):921-939.
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Hypomorphic mutations in POLR3A are a frequent cause of sporadic and recessive spastic ataxia. Brain. 2017 06 01; 140(6):1561-1578.
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BRF1 mutations alter RNA polymerase III-dependent transcription and cause neurodevelopmental anomalies. Genome Res. 2015 Feb; 25(2):155-66.
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Mutations in genes encoding subunits of RNA polymerases I and III cause Treacher Collins syndrome. Nat Genet. 2011 Jan; 43(1):20-2.