"Creatine Kinase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A transferase that catalyzes formation of PHOSPHOCREATINE from ATP + CREATINE. The reaction stores ATP energy as phosphocreatine. Three cytoplasmic ISOENZYMES have been identified in human tissues: the MM type from SKELETAL MUSCLE, the MB type from myocardial tissue and the BB type from nervous tissue as well as a mitochondrial isoenzyme. Macro-creatine kinase refers to creatine kinase complexed with other serum proteins.
Descriptor ID |
D003402
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MeSH Number(s) |
D08.811.913.696.640.150
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Concept/Terms |
Creatine Kinase- Creatine Kinase
- Kinase, Creatine
- ATP Creatine Phosphotransferase
- Creatine Phosphotransferase, ATP
- Phosphotransferase, ATP Creatine
- Creatine Phosphokinase
- Phosphokinase, Creatine
- ADP Phosphocreatine Phosphotransferase
- Phosphocreatine Phosphotransferase, ADP
- Phosphotransferase, ADP Phosphocreatine
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Below are MeSH descriptors whose meaning is more general than "Creatine Kinase".
Below are MeSH descriptors whose meaning is more specific than "Creatine Kinase".
This graph shows the total number of publications written about "Creatine Kinase" by people in this website by year, and whether "Creatine Kinase" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1994 | 1 | 0 | 1 |
1998 | 0 | 1 | 1 |
2001 | 0 | 2 | 2 |
2013 | 0 | 1 | 1 |
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Below are the most recent publications written about "Creatine Kinase" by people in Profiles.
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Recessive TRAPPC11 mutations cause a disease spectrum of limb girdle muscular dystrophy and myopathy with movement disorder and intellectual disability. Am J Hum Genet. 2013 Jul 11; 93(1):181-90.
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Mutations in CAV3 cause mechanical hyperirritability of skeletal muscle in rippling muscle disease. Nat Genet. 2001 Jul; 28(3):218-9.
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Control of oxidative phosphorylation in skeletal muscle. Biochim Biophys Acta. 2001 Mar 01; 1504(1):12-9.
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Permeabilized cell and skinned fiber techniques in studies of mitochondrial function in vivo. Mol Cell Biochem. 1998 Jul; 184(1-2):81-100.
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The influence of the cytosolic oncotic pressure on the permeability of the mitochondrial outer membrane for ADP: implications for the kinetic properties of mitochondrial creatine kinase and for ADP channelling into the intermembrane space. Mol Cell Biochem. 1994 Apr-May; 133-134:85-104.
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[ATP-metabolizing enzymes in suspensions of isolated coupled rat brain mitochondria]. Biomed Biochim Acta. 1987; 46(5):331-40.
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Cause and consequences of dynamic compartmentation of adenine nucleotides in the mitochondrial intermembrane space in respect to exchange of energy rich phosphates between cytosol and mitochondria. Biomed Biochim Acta. 1987; 46(8-9):S545-8.